工频磁场离体生物效应辐照系统及其性能

Exposure Setup of 50 Hz Magnetic Field Applied in Studying of the Bioeffects and Its Characters

采用理论设计与实验测量相结合,根据细胞培养箱和细胞培养板的尺寸等实验要求设计了50 Hz磁场辐照系统,并用二维检测平台测试了该辐照系统的性能。通过合理的选择亥姆霍兹线圈的尺寸和匝数等,适当调节信号输出幅度和功率放大器放大倍数,设计制造的50 Hz磁场辐照系统的磁感应强度大小为B=0.805 2I m T,磁场不均匀度小于1%的区域为｜x｜〈5 cm;｜y｜〈5 cm;｜z｜〈4 cm,不均匀度小于5%的区域为｜x｜〈10 cm;｜y｜〈10 cm;｜z｜〈5 cm;磁感应强度的变化范围为0-1.5 m T。50 Hz磁场辐照系统的线圈导线温度先升高,经过一定时间后能达到稳定,并且在辐照区域的温度等于空间温度。该辐照系统简单经济,操作方便,可长时间工作,磁场变化范围大且分布均匀区域较大,可为50 Hz磁场辐照离体细胞生物效应的相关研究提供一定范围的稳定磁场。

To study the dose-effect relationship between magnetic field and its biological effects,it ＇s necessary to establish the stable and uniform magnetic field that is able to work long time. Using theoretical analysis and experimental test,exposure setup of 50 Hz magnetic field was designed according to the experimental requirements such as the sizes of cell incubator and tissue culture plates. The performance of the setup was tested with a two-dimensional removable platform. By choosing probable parameters of the coil and the output of source and amplifier,the magnetic induction was B = 0. 805 2I m T,and it could change from 0 m T to 1. 5 m T. The 1% deviation area was ｜x｜ 5 〈cm;｜ y｜ 〈5 cm;｜z｜〈 4 cm,and the 5% deviation area was ｜x｜ 〈10 cm;｜ y｜〈10 cm;｜ z｜ 〈5 cm. The temperature of the coils was firstly rising and then achieved stability after short time. Temperature of irradiation area was equal to the room temperature. Results showed that the exposure setup was economical and easily handled,so it could produce stable magnetic field in certain area for the in vitro experiments on the effect of 50 Hz magnetic field exposures.