幽门螺杆菌感染与大肠肿瘤的相关性研究

Study on the Relationship between Helicobacter Pylori Infection and Colorectal Neoplasia

目的:研究幽门螺杆菌(H.pylori)感染与大肠肿瘤的关系。方法:回顾性收集2011年1月-2015年8月于本院同期完成电子结肠镜及14C尿素呼气试验或13C尿素呼气试验的244例患者的临床资料,按照电子结肠镜结果分为大肠肿瘤组(观察组)和正常组(对照组),比较两组的H.pylori感染情况。结果:观察组H.pylori感染阳性率明显高于对照组,比较差异有统计学意义(P<0.05)。结论:H.pylori感染与大肠肿瘤之间存在相关性,H.pylori感染可能增加大肠肿瘤发生的风险。

Objective： To investigate the relationship between the infection of Helicobacter pylori （ H.pylori ） and colorectal neoplasia.Method： The clinical data of 244 patients who completed 14C urea breath test or 13C urea breath test at the same period in our hospital from January 2011 to Augnst 2015 were col]ected.They were divided into the colorectal neoplasia group （ observation group ） and the normal group （ control group ） according to the results of electronic eelonoscope.The situation of H.pylori infection was compared between the two groups.Result： The positive rate of H.pylori infection in the observation group was higher than that in the control group, the difference was statistically significant （P〈0.05） .Conclusion： H.pylori infection may be related to the colorectal neoplasia.H.pylori infection may increase, the risk of colorectal neoplasia.