超高效液相色谱质谱/质谱法的测定广东地区市售8类动物源食品中氯霉素残留的调查分析

Survey and Analysis of Chloramphenicol Residues in 8 Kinds of Animal-origin Foods Purchased from Markets by UPLC-MS/MS

随机抽取了市售的牛肉、虾肉、蜂蜜、贝类、鸡肉、猪肉、牛奶及鱼肉食品等8类动物源食品样品1709份,采用超高效液相-质谱法对食品中氯霉素的含量进行了检测调查分析。方法在0.5-50μg/L范围内呈良好的线性关系,相关系数R为0.997,检出限为0.1μg/kg,回收率在75%-120%之间。样品中除鸡肉、猪肉、牛肉、虾肉未检出外,其它种类的样品中均有检出。蜂蜜、贝类、牛奶及鱼肉样品中氯霉素的检出率分别为0.86%、1.41%、0.62%和0.39%;其含量范围分别为0.0-1.8μg/kg、0.0-4.5μg/kg、0.0-0.5μg/kg和0.0-2.6μg/kg。调查结果表明,市场上食品中氯霉素存在一定程度的污染,相关部门应该引起重视,并加强食品中违禁药物的监测工作。

1709 samples were collected randomly from markets including 8 kinds of animal-origin foods such as beef, shrimp, honey, shellfish, chicken, pork, milk and fish samples, ultra-performance liquid chromatography-tandem mass spectrometry（UPLC-MS/MS） was applied to detect the levels of chloramphenicol in food samples. The method detection ranges were 0.5-50 μg/L, and the correlation coefficients was 0.997. The detection limit was achieved as 0.1 μg/kg, recovery range of chloramphenicol was 75 %-120 %. Expect chicken, pork, beef and shrimp samples, other kinds of samples were detected. Chloramphenicol was detected in honey, shellfish, milk and fish samples with detection rates of 0.86 %, 1.41 %, 0.62 % and 0.39 %, respectively. And their concentration ranges were 0.0-1.8, 0.0-4.5, 0.0-0.5 and 0.0-2.6 μg/kg. The results showed the food samples were contaminated with chloramphenicol to some extent from markets, and related departments should pay attention on it and strengthen the monitoring of illicit drugs in food.