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EGFR表达对晚期非小细胞肺癌化疗患者预后状况的预测价值

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摘要 目的:探讨EGFR在晚期非小细胞肺癌化疗患者中的表达与预后的关系。方法:选取本院收治的非小细胞肺癌化疗患者50例为观察组,同期行手术治疗的部分肺良性病变患者23例为对照组。分析两组患者肺组织中EGFR的表达情况。结果:观察组中EGFR的表达百分数明显高于对照组,差异有统计学意义(P<0.05);不同组织类型患者EGFR的表达差异无统计学意义(P>0.05);Ⅳ期患者EGFR的表达百分数明显高于Ⅲ期患者,差异有统计学意义(P<0.05);中-高分化者EGFR的表达百分数明显高于低分化,差异有统计学意义(P<0.05);EGFR表达水平<50%者5年生存率明显高于EGFR表达水平≥50%者,差异有统计学意义(P<0.05)。结论:EGFR表达在晚期NSCLC化疗患者中明显提高,与患者分期及分化程度密切相关,且可作为判断患者预后的指标之一。
作者 王胜德
出处 《中国医学创新》 CAS 2016年第3期138-139,共2页 Medical Innovation of China
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