围术期舒芬太尼复合罗哌卡因蛛网膜下腔镇痛对患者应激反应的影响

Influence of sufentanil combined ropivacaine treatment of subarachnoid analgesia of perioperative in patients' stress response

目的探讨围术期舒芬太尼复合罗哌卡因蛛网膜下腔镇痛对患者应激反应的影响。方法选择2013年12月~2014年12月在我院腰硬联合阻滞下行腹部手术患者200例,分为观察组和对照组,两组均行腰硬联合阻滞,治疗组蛛网膜下腔给予舒芬太尼5μg＋1.5mg罗哌卡因2.5m L,对照组蛛网膜下腔给罗哌卡因3mg,观察两组感觉阻滞、运动阻滞及镇静效果。结果观察组感觉阻滞、运动阻滞Bromage评分及镇静Ramsay评分均显著优于对照组,差异有统计学意义（P〈0.05）。结论腰硬联合阻滞应用舒芬太尼复合罗哌卡因,镇痛强度大,对患者全麻诱导应激反应的具有一定的抑制作用,且具有起效时间快、镇痛时间长等优点,应该作为一种较好的镇痛方法应用于临床中。

Objective To study the influence of sufentanil combined ropivacaine in the treatment of subarachnoid analgesia of perioperative in patients＇ stress response. Methods 200 patients with abdominal operation under combined spinal-epidural anaesthesia,who were selected in our hospital from December 2013 to December 2014,were divided into observation group and control group.The two groups were treated with combined spinalepidural anaesthesia,observation group was treated with sufentanil（5μg＋1.5mg） combined ropivacaine 2.5m L in subarachniod,while control group was treated with ropivacaine 3mg in subarachniod.To observe the sensory block,motor block,and sedative effect between the two groups. Results The Bromage score of sensory block and motor block,the Ramsay score of sedative in observation group were observation better than which in control group,the difference had statistical significance（P〈0.05）. Conclusion Sufentanil combined ropivacaine in the treatment of combined spinal-epidural anaesthesia has great analgesia intensity,has certain inhibition in induction of general anesthesia patients＇ stress response,has the advantages of rapid time on taking effect and longer analgesia time and so on,should be used on clinical as a better analgesia method.