超声引导下穿刺活检在颈部及锁骨上窝淋巴结病变诊断中的应用价值

Value of ultrasound-guided core-needle biopsy in diagnosing of neck and supraclavicular fossa lymphadenopathy

目的探讨超声引导下穿刺活检术在颈部及锁骨上窝淋巴结病变诊断中的应用价值。方法回顾性分析我科120例超声引导下的颈部及锁骨上窝淋巴结的活检结果,与常规彩色多普勒超声作对比,以取得组织所提供的肯定病理诊断或术后病理为最终诊断标准。结果 120例患者中,116例所取出目标组织能做出明确组织病理诊断,穿刺确诊率为96.7%。超声引导下穿刺活检对诊断颈部及锁骨上窝淋巴结病变的灵敏度、特异度和准确度为98%、96%、97%,常规彩色多普勒超声诊断的相应指标分别为81%、90%、87%,灵敏度、准确度差异有统计学意义(P<0.05)。结论超声引导下穿刺活检颈部及锁骨上窝淋巴结,可显著提高淋巴结病变诊断的准确性,且微创并发症低,可作为临床诊断颈部及锁骨上窝淋巴结病变的首选方法。

Objective To investigate the value of ultrasound-guided core-needle biopsy in diagnosis of neck and supraclavicular fossa lymphadenopathy. Methods 120 patients with neck and supraclavicular fossa lymphadenopathy underwent ultrasound-guided biopsy used coarse needle. Final diagnosis was made based on pathology taken by core-needle biopsy or postoperative. Results There were 116 satisfied materials in 120 cases, from which definite histologic diagnosis could be given. The satisfactory rate of sampling was 96.7%.The sensitivity, specificity and accuracy of ultrasound-guided core-needle biopsy in diagnosis of neck and supraclavicular fossa lymphadenopathy were 98%,96%,97%. However, the sensitivity, specificity and accuracy index of US in that was 81%, 90%,87%respectively.There were significant difference in sensitivity, accuracy between the Ultrasound-guided Coreneedle Biopsy and US（P〈0.05）. Conclusion Ultrasound-guided Core-needle Biopsy is sensitive and accurate in diagnosis of neck and supraclavicular fossa lymphadenopathy with a lower incidence of complication,it is an effective technique in confirming the diagnosis of neck and supraclavicular fossa lymphadenopathy.