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TLR4与β2GPI/抗β2GPI复合物在动脉粥样硬化中的作用研究

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摘要 动脉粥样硬化（Atherosclerosis,AS）所引起的血栓形成及心血管疾病是目前全世界导致人类死亡的主要原因,对人类的生存和生活质量是一种巨大的威胁和破坏。弗雷明汉研究提出了一系列动脉粥样硬化的危险因素,例如高胆固醇血症、高血压、吸烟、肥胖和家族史等,但这些危险因素已不足以解释该病的发生发展,有关AS的自身免疫因素越来越受到关注。
作者 王婷 周红
机构地区 江苏大学医学院
出处 《中国免疫学杂志》 CAS CSCD 北大核心 2016年第2期262-266,共5页 Chinese Journal of Immunology
基金 国家自然科学基金资助项目(No.81370614)
关键词 PI TLR4 弗雷明汉研究 抗磷脂综合征 自身免疫性疾病 自身免疫因素 高胆固醇血症 心血管疾病 巨噬细胞 血管内皮细胞
分类号 R543.5 [医药卫生—心血管疾病]
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参考文献30

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二级参考文献41

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共引文献13

中国免疫学杂志
2016年 第2期

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