睑板腺红外线成像装置两种图像分析方法的比较

Comparison of the two methods of image analysis of infrared meibography

目的比较睑板腺红外线成像装置的两种图像分析方法。方法用睑板腺红外线成像装置观察睑板腺功能障碍(MGD)患者(MGD组,32例)和健康对照者(对照组,28例)的上睑板腺形态,按上睑板腺缺失面积计算评分。采用两种图像分析方法比较两组上睑板腺腺体占比(即睑板腺体面积与睑板面积之比)。结果 MGD组睑板腺缺失面积评分为1分、2分和3分的比例均高于对照组。两种图像分析方法结果均显示:MGD组上睑板腺体占比平均值低于对照组,差异有统计学意义(t=-6.26,P=0.00;t=-7.69,P=0.00)。结论睑板腺红外线成像装置的两种图像分析方法均能直观地反映睑板腺情况,与封闭曲线法相比,中央矩形法操作简单,能更快速准确反映睑板腺情况,可作为一种有效的辅助手段协助临床医生诊断睑板腺功能障碍。

Objective To compare the two methods of image analysis of infrared meibography. Methods The mor- phology of meibomian glands of 32 patients with meibomian gland dysfunction （MGD group） and 28 healthy cases as control group were imaged using the infrared meibography. A meibomian gland dropout score due to gland loss was obtained. Used two methods of image analysis to compare the ratio of the total meibomian gland area and the total meibomian area in all subjects. Results The proportion of 1, 2 and 3 scores of the meibomian gland dropout score in the MGD group was higher than those in the control group. Two methods of image analysis results also showed that the mean ratio of the meibomian gland area to the total meibomian area in the MGD group was lower than the control group, the difference was statistically significant（t=-6.26,P=0.00; t=-7.69,P=0.00）. Conclusion Both of the two methods of image analysis about infrared meibography can reflect the meibo- mian gland intuitively. Compared with the operation method of closed curve, the method of central rectangle is faster, more sim- ple and accurate in reflecting the meibomian gland, which can be used as an effective auxiliary means to help clinical doctors in diagnosing meibomian gland dysfunction.