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艾塞那肽与甘精胰岛素治疗口服降糖药物效果不佳的2型糖尿病患者的疗效观察 被引量:5

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摘要 2型糖尿病属于多因素作用后导致的代谢性疾病,临床上以慢性高血糖为特征,在我国,超重者糖尿病的发病率是非超重者的1.5倍,超重和肥胖已是我国糖尿病患病率急剧上升的重要原因之一。肥胖患者的体内存在胰岛素抵抗和高胰岛素血症,胰岛素对肝糖原合成的抑制和对葡萄糖的利用率显著降低,周围组织对葡萄糖的利用发生障碍,非酯化脂肪酸上升。近些年研究发现,胰高糖素分泌过多可导致糖尿病的发生,艾塞那肽属于肠促胰岛素的类似物。可与胰高血糖素样肽-1受体结合发挥降糖作,,受到了业内人士的广泛关注。本研究从降糖效果、对胰岛B细胞功能的影响情况及对体质量的影响进行了比较研究.现报道如下。
出处 《中国现代医药杂志》 2016年第1期46-48,共3页 Modern Medicine Journal of China
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