美沙酮替代治疗门诊HIV阴性男性患者的生命质量及影响因素

QUALITY OF LIFE AND ITS INFLUENCING FACTORS AMONG MALE WITH HIV POSITIVE OFMETHADONE CLINICS

目的：了解广西美沙酮替代治疗门诊人类免疫缺陷病毒（HIV）阴性男性患者的生命质量现状和探讨相应的影响因素。方法：采用自填式调查问卷方式对670例患者的一般情况及生命质量进行调查及统计分析。结果：广西美沙酮替代治疗门诊670例患者中HIV阴性且为男性患者占66.42%（445/670）,无工作、有工作的患者生命质量总分均数分别为（145.69±28.52）分、（152.24±27.41）分;独居、非独居的患者生命质量总分均数分别为（140.78±26.46）分、（150.36±28.14）分;未婚、已婚、离异与丧偶的患者生命质量总分均数分别为（146.56±28.41）分、（152.55±27.28）分、（144.32±29.23）分;月收入水平（元）〈100元、100~元、500~元、≥1 000元的患者生命质量总分均数分别为（144.66±29.66）分、（142.54±28.38）分、（153.66±25.01）分、（154.77±26.15）分,差异均具有统计学意义（P〈0.05）。多元线性逐步回归分析：进入生命质量总分模型的因素是月收入水平和居住状况。结论：月收入水平和居住状况可能是美沙酮替代治疗门诊HIV阴性男性患者生命质量高低的重要影响因素。

Objective： To explore the quality of life of male patients with HIV positive treated by Methadone rather than out-patient treatment, and to identify its related factors. Methods： We conducted a survey to investigate subjects＇ demographic characteristics and the quality of life by using a self-report questionnaire. Results： The total scores＇ mean of quality of life between the unemployment and employment patients were （145.69±28.52）, （152.24±27.41）（ P 〈0.05） ; the total scores＇ mean of quality of life between living alone and not living alone were （140.78±26.46）, （150.36± 28.14）（ P 〈0.05）; the total scores＇ mean of quality of life of unmarried, married and divorced and widow patients were（146.56 ± 28.41）, （152.55 ± 27.28）, （144.32±29.23）（ P 〈0.05）; the total scores＇ mean of quality of life monthly earnings （RMB）% 100,100-,500-,≥1 000 patients were（144.66±29.66）,（142.54±28.38）, （153.66±25.01）, （154.77± 26.15） （ P 〈0.05）. Multivariate analysis, variables of monthly earnings （Yuan） and living conditions were stated in the multivariate model. Conclusion. Living conditions and income level were important factors for patients＇ quality of life.