聚桂醇泡沫硬化剂治疗下肢静脉曲张的临床研究

Clinical Study of the Effect of Lauromacrogol Foam Sclerosant in the Treatment of Lower Extremity Varicose Veins

目的探讨聚桂醇泡沫硬化剂治疗下肢静脉曲张的临床效果。方法整群选取2013年5月—2015年6月该院收治的88例下肢静脉曲张患者的病例作为研究对象,采取回归分析法,分为对照组与观察组各44例,对照组主要使用大隐静脉高位结扎和抽剥手术等进行治疗,观察组主要使用聚桂醇泡沫硬化剂治疗,通过对两组患者的手术时间、术中出血量、切口长度、术后下床时间、住院时间等进行比较。结果对照组的总有效率为89.43%,观察组的总有效率95.43%,通过两组患者的临床效果进行比较,观察组的效果要比对照组显著,两组患者差异有统计学意义(P<0.05)。其中观察组的手术时间、术中出血量、切口长度、术后下床时间、住院时间等都要比对照组低,两组患者差异有统计学意义(P<0.05)。结论对下肢静脉曲张的患者进行聚桂醇泡沫硬化剂治疗,在临床中取得了良好的效果,该方法可以有效的降低患者的手术时间、住院时间,具有创伤少、恢复快、不容易复发的特点,值得临床推广使用。

Objective To study the effect of lauromacrogol foam sclerosant in the treatment of lower extremity varicose veins. Methods 88 cases with lower extremity varicose veins admitted in our hospital from May 2013 to June 2015 were se-lected as the subjects and divided into the control group and the observation group with 44 cases in each according to the regression analysis method. Patients in the control group were mainly treated by high ligation and stripping of great saphe-nous vein, while those in the observation group were mainly treated by lauromacrogol foam sclerosant. And the operation time, intraoperative blood loss, length of incision, postoperative ambulation time, length of hospital stay of the two groups were compared. Results The total effective rate was much better in the observation group than that in the control group （95.43%vs 89.43%）, the difference between the two groups was statistically significant （P〈0.05）. Compared with the control group, the observation group had shorter operation time, less intraoperative blood loss, shorter length of incision, earlier postoperative ambulation time and shorter length of hospital stay, with statistically significant differences （P〈0.05）. Conclu-sion For lower extremity varicose veins, lauromacrogol foam sclerosant has good clinical effect, which can effectively reduce the operation time, and length of hospital stay, with small trauma, rapid recovery, and the disease is not easy to relapse, so it is worthy of clinical use.