老年患者手术麻醉应用瑞芬太尼和芬太尼静脉麻醉的疗效比较

Comparison of Efficacy of Intravenous Anesthesia with Remifentanil and Fentanyl in Elderly Surgical Patients

目的比较应用瑞芬太尼和芬太尼两种静脉麻醉方法 ,对于老年手术患者起到的临床麻醉效果。方法整群选取2013年1月—2014年7月该院实施过麻醉术的60例老年患者,根据随机将选取的60例老年患者分为观察组和对照组,两组各30例,其中观察组30例应用瑞芬太尼麻醉,对照组30例应用芬太尼麻醉,比较两组静脉麻醉临床效果。结果观察组患者(自主呼吸恢复时间9.1±3.2;苏醒时间14.6±2.8;定向力恢复时间14.2±3.1)min,均低于对照组(自主呼吸恢复时间12.8±3.6;苏醒时间20.9±4.3;定向力恢复时间24.9±8.7)min;两组比较差异有统计学意义(P<0.05)。结论应用瑞芬太尼静脉麻醉对老年手术患者,其使用时具有较高安全性,且醒麻时间较短,适宜临床应用推广。

Objective To compare the anesthetic effect of remifentanil and fentanyl applied in elderly surgical patients. Methods 60 elderly surgical patients who experienced anesthesia in our hospital from January 2013 and July 2014 were se-lected and randomly divided into observation group and control group with 30 in each one. The 30 patients in the observa-tion group were given anesthesia with fentanyl while the other 30 in the control group adopted anesthesia with remifentanil. The clinical outcome of the intravenous anesthesia was compared between the two groups. Results The recovery time of spontaneous respiration, analepsia time, orientation recovery time of the patients were （9.1 ±3.2）min, （14.6 ±2.8）min, （14.2 ± 3.1）min respectively in the observation group, all lower than that in the control group, which were （12.8±3.6）min, （20.9±4.3） min, （24.9±8.7）min respectively, and the differences between the two groups were statistically significant, P〈0.05. Conclu-sion Remifentanil intravenous anesthesia for elderly surgical patients is of high safety and shorter analepsia time, therefore it is suitable for clinical promotion.