三溴乙醇对小鼠麻醉效果的研究

Anesthetic Effects of Tribromoethanol on Mice

为研究三溴乙醇对小鼠的麻醉效果,使用5组不同剂量三溴乙醇（200、350、500、800和1000 mg/kg）分别腹腔注射小鼠,进行小鼠麻醉。结果表明,200 mg/kg三溴乙醇腹腔注射小鼠,麻醉效果很差,小鼠未达到麻醉状态而持续动弹,350-800 mg/kg三溴乙醇腹腔注射小鼠能达到很好的麻醉效果。

To study anesthetic effects of tribromoethanol on mice, the tribromoethanol were processed intraperitoncal injection with five groups of different dose gradients （200、350、500、800 and 1 000 mg/kg） respectively, and then the anesthesia onset time and duration time were compared. Results showed that the tribromoethanon at dosage of 200 mg/kg showed the worst anesthesia effect, the mice were unanesthetized and kept moving; intraperitoncal injection of tribromoethanol at dosage of 350~800 mg/kg had moderate anesthesia duration and adequate anesthesia depth, which were suitable anesthesia for mice.