2型糖尿病患者的干眼患病情况及其相关影响指标

Study on prevalence of xerophthalmia in patients with type 2 diabetes mellitus and related factors influencing xerophthalmia

目的:比较2型糖尿病(2-DM)患者与非2-DM人群干眼的患病率差异,并分析影响干眼的2型糖尿病相关指标。方法:选取2014-03/2015-05于我院内分泌科就诊的2-DM者80例(观察组),门诊体检中心的正常体检者98例(对照组)。参照WHO干眼诊断标准,统计分析两组患者干眼的患病率。将观察组患者分别依据糖尿病病程、年龄、性别以及血糖控制情况分组,组内分析其干眼患病率有无差别。结果:观察组患者干眼的患病率为49%(39/80),显著高于对照组(29%),差异有统计学意义(P<0.01)。2-DM患者随年龄、病程以及血糖水平增加,其干眼患病率升高,差异有统计学意义(P<0.05)。不同性别患者之间干眼患病率无统计学差异(P>0.05)。结论:2-DM患者干眼患病率高于正常人群,且随患者年龄、病程及血糖水平增加而升高,但不同性别间其患病率无明显差异。

AIM：To comparae the difference on the prevalence of xerophthalmia in patients with type 2 diabetes mellitus（2-DM） or without 2-DM,and analyse the related factors which can influence the prevalence of xerophthalmia.·METHODS：One hundred and seventy-eight patients during March 2014 to May 2015 were selected,in which eighty cases were with 2-DM（as observation group）,ninty-eight cases were without 2- DM（as control group）.Xerophthalmia was diagnosed according to WHO standard.Statistically analyze the incidence of xerophthalmia in the two groups.The patients in the observation group were grouped according to the duration of diabetes,age,gender and blood glucose level,and the difference of xerophthalmia prevalence in the groups were analyzed.·RESULTS：The prevalence of xerophthalmia in the observation group was 49%（39/80）,which was higher than that in the control group（29%） and the difference was statistically significant（P0.01）.The prevalence of xerophthalmia in patients with 2-DM was increased with age,duration and blood glucose levels,the differences were statistically significant（P0.05）.There was no significant difference in the prevalence of xerophthalmia between different genders（P0.05）.·CONCLUSION：The prevalence of xerophthalmia in 2-DM patients is higher than that in normal group,and increases with age,duration and blood glucose level.However,there is no significant difference in the prevalence of xerophthalmia between different genders.