地佐辛复合舒芬太尼在腹腔镜子宫肌瘤术后静脉镇痛中的效果观察

Effect Observation of Dezocine Combined with Sufentanil in the Intravenous Analgesia After Laparoscopic Hysteromyomectomy

目的观察地佐辛复合舒芬太尼在腹腔镜子宫肌瘤术后静脉镇痛的效果及安全性。方法选取在本院择期行腹腔镜子宫肌瘤切除术的60例患者,随机分为观察组和对照组,每组30例。观察组使用地佐辛复合舒芬太尼进行术后静脉自控镇痛,对照组仅使用舒芬太尼进行术后静脉镇痛,观察并记录两组的VAS评分、Rasmay镇静评分、BCS评分以及不良反应发生情况。结果观察组和对照组术后2 h、6 h、12 h、24 h和48 h的VAS评分、Rasmay镇静评分、BCS评分均无统计学差异(P>0.05)。观察组不良反应发生率显著低于对照组(20.0%vs 46.7%),差异有统计学意义(P<0.05)。结论地佐辛复合舒芬太尼用于腹腔镜子宫肌瘤术后静脉镇痛效果良好,安全性及患者舒适度高,值得在临床应用。

Objective To observe the effect and safety of dezocine combined with sufentanil in the intravenous analgesia after laparoscopic hysteromyomectomy. Methods Sixty patients underwent laparoscopic hysteromyomectomy in our hospital were selected and randomly divided into observation group and control group, with 30 cases in each group. The observation group was given dezocine combined with sufentanil for patient-controlled intravenous analgesia（PCIA）, and the control group was only given sufentanil for PCIA. The VAS score, Rasmay sedation score, BCS score and adverse effects were observed and recorded. Results No significant difference was found in the VAS score, Rasmay sedation score and BCS score of observation group and control group after 2 h, 6 h, 12 h, 24 h, 48 h of the treatment, P〈0.05. The incidence of adverse reactions of observation group was significantly lower than that of control group（20.0% vs46.7%）, with statistical difference（P〈0.05）. Conclusions Dezocine combined with sufentanil have good effect in the intravenous analgesia after laparoscopic hysteromyomectomy, with high safety and comfort, which is worthy of application in clinic.