小儿反复呼吸道感染非急性期证素分布及组合规律的文献研究

Study on the Distribution, Combination Rule of TCM Syndrome Factors of RRTI in Non Acute Phase Based on Document Data

目的:基于文献研究小儿反复呼吸道感染非急性期证素的分布及组合规律,对其基础证的主次症进行筛选。方法:收集近20年小儿反复呼吸道感染非急性期的相关文献并整理,运用频率描述及两分类Logistic回归分析的方法进行统计分析。结果:共纳入合格文献158篇,共计339条记录。小儿反复呼吸道感染非急性期的病位证素以肺、脾为主,病性证素以气虚、阴虚、痰及血瘀为主;其组合形式以三、四证素组合最为常见,组合类型则以肺+脾+气虚、肺+气虚、肺+气虚+血瘀及肺+脾+气虚+血瘀最为常见;其基础证主要有肺脾气虚证及肺气虚证。肺脾气虚证的主症为纳差、自汗、大便溏及久咳,次症为乏力、面色萎黄及面色少华。肺气虚证的主症为恶风、恶寒、面白,次症为语声低弱、久咳、面色少华、自汗。结论:小儿反复呼吸道感染非急性期证素分布及组合存在一定的规律,可为进一步研究提供参考。

Objective： To study the distribution, combination rule of TCM syndrome factors and characteristics of basic syndromes of RRTI in non acute phase based on document data. Methods： The document data was gathered by way of document database index in resent 20 years. The data was analyzed by description and binary logistic regression. Results： There were 158 documents and 339 items used for analysis. The most common location syndrome factors of RRTI were lung and spleen, and the most common nature syndrome factors were Qi-deficiency, Yin-deficiency, the phlegm and the blood stasis. The most common combinative models of RRTI were the combination of three syndrome factors and the combination of four syndrome factors. The most common combinative types of syndrome factors were the combination types of lung＋spleen＋Qi-deficiency, lung＋Qi- deficiency, lung＋Qi-deficiency＋blood-stasis and lung＋spleen＋Qi-deficiency＋blood-stasis. The basic syndromes of RRTI were dual Qi deficiency of the lung-spleen syndrome, Qi deficiency of the lung syndrome. The main symptoms in dual Qi deficiency of the lung-spleen syndrome were anorexia, spontaneous sweating, diarrhea and prolonged cough; the concurrent symptoms in dual Qi deficiency of the lung-spleen were fatigue, sallow com- plexion, and lusterless complexion. The main symptoms in Qi deficiency of the lung syndrome were aversion to chill, aversion to wind and whitish complexion, and the concurrent symptoms in Qi deficiency of the lung were weak voice, prolonged cough, lusterless complexion and spontaneous sweating. Conclusion： There was certain rule on distribution and combination of TCM syndrome factors in RRTI with non acute phase; its results can supply the basic theories for the next study.