从脾胃论治冠心病心绞痛患者40例临床观察

Clinical Observation of 40 Patients with Angina Pectoris Treated with Pi-Wei Theory

目的观察调脾通络颗粒治疗冠心病心绞痛的临床疗效及对血脂、血浆纤维蛋白原(FIB)水平的影响。方法将120例心绞痛患者随机分为对照组(40例)、活血组(40例)及调脾组(40例)。对照组采用西医常规治疗,活血组在常规治疗基础上加用养心氏片,调脾组在常规治疗基础上加用调脾通络颗粒,疗程为28 d。观察3组临床疗效、治疗前后血脂及FIB水平的变化。结果调脾组临床疗效(92.5%)优于对照组和活血组(92.5%,75.0%),差异有统计学意义(P<0.05)。3组血脂指标及纤维蛋白原治疗后均有改善(P<0.05),而调脾组改善优于对照组和活血组(P<0.05)。结论调脾通络颗粒治疗心绞痛疗效可靠,能够调节脂质代谢,稳定动脉粥样硬化斑块,减轻患者高凝状态。

ObJecttve To observe the effect of Tiaopi Tongluo granule（TTG） in treating patients with angina pectoris and its influence on serum lipids and fibrinogen. Methods The patients with angina pectoris were randomly divided into three groups：Control group treated with routine western medicine,treatment group 1 treated with routine treatment plus Yangxinshi tablet,treatment group 2 trea- ted with routine treatment plus TTG for 28 days. The clinical efficacy, traditional Chinese medicine（TCM） symptom score, levels of serum lipid and fibrinogen were observed. Results The clinical effect in treatment group 2 was better than control group and blood activating group. After treatment, the levels of serum lipids and fibrinogen in three groups were improved,while the effect in treatment group 2 was better than that in control group and treatment group 1. Conclution TTG has a reliable clinical therapeutic effect on an- gina pectoris, which can regulate the lipid metabolism, stabilize atherosclerotic plaque, and relieve the high coagulation state.