不同时间窗及疗程的高压氧治疗对急性脑梗死的影响

Influence of Acute Cerebral Infarction and Treatment of Different Time Windows Hyperbaric Oxygen Therapy

目的探讨不同时间窗及疗程的高压氧对急性脑梗死疗效的影响。方法对我院2013年7月至2015年1月间接治的112例急性脑梗死患者按从发病到高压氧治疗的时间窗及疗程分为四组,每组28例。对各组患者在高压氧治疗后分别进行日常生活活动能力（ADL）评分及脑电图检查,并进行各组之间的比较。结果在行同样疗程的高压氧治疗中,越早进行高压氧治疗,患者的日常生活活动能力（ADL）评分及脑电图结果越好,差异有统计学意义（P〈0.05）。结论高压氧治疗时间窗对首次发病的急性脑梗死患者疗效具有重要影响,开始治疗时间越早则疗效越佳,以发病后24 h内行高压氧治疗疗效最佳,24~72 h内干预则疗效次之,超过72 h则疗效大幅降低。

Objective To investigate the effect of hyperbaric oxygen on acute cerebral infarction in different time windows and treatment.Methods 112 patients with acute cerebral infarction were divided into four groups according to the time window and the course of treatment,28 cases in each group.After hyperbaric oxygen therapy,the daily activity of daily living（ADL） score and EEG were examined and compared between groups.Result The same line course of hyperbaric oxygen therapy,hyperbaric oxygen therapy sooner,the patient’s activities of daily living（ADL） score and EEG better result,the difference was statistically significant（P〈0.05）.Conclusion Hyperbaric oxygen therapy time window has an important influence on the treatment of first onset of acute cerebral infarction patients,the early treatment time is better,with the incidence of 24 h after treatment with hyperbaric oxygen therapy,24-72 h within the efficacy of intervention,more than 72 h.