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血小板/淋巴细胞比值与冠状动脉狭窄程度的关系探讨 被引量:5

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摘要 目的研究血小板与淋巴细胞比值(PLR)与冠状动脉狭窄程度的关系,探讨PLR对冠心病病人冠状动脉病变严重程度的预测作用。方法 584例病人行冠状动脉造影,对其中确诊为冠心病的464例进行冠脉Gensini评分,并将其分为低分组(Gensini积分〈30分,120例)和高分组(≥30分,244例),检测血小板与淋巴细胞水平,应用SPSS19.0软件进行统计分析。结果冠心病病人血清PLR水平高于非冠心病病人(P〈0.001)。高Gensini积分组PLR水平高于低Gensini积分组(P〈0.001),相关性分析显示PLR水平与Gensini积分呈正相关(r=0.163,P〈0.001),多因素Logistic回归分析显示高PLR和高GGT水平是高Gensini积分的独立危险因素。受试者工作特征曲线(ROC曲线)显示PLR的曲线下面积是0.592(95%CI:0.545~0.640),当PLR诊断临界值取122.68时,其诊断效率最高,敏感性为46.7%,特异性为62.6%。结论 PLR与冠心病严重程度有相关性,在临床上可作为预测冠状动脉狭窄程度的指标。
作者 杜玥 雷红
出处 《中西医结合心脑血管病杂志》 2015年第18期2103-2106,共4页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
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