103例泌尿生殖道支原体感染及药物敏感性试验结果分析

目的分析泌尿生殖道炎症患者支原体的感染情况及其对抗菌药物的药物敏感性试验（简称药敏试验），方法采用珠海黑马生物工程有限公司提供的支原体培养鉴定及药敏试剂盒进行检测。结果103例患者中，支原体阳性51例，阳性率49．51％。解脲支原体（Uu），人型支原体（Mh）及Uu＋Mh混合感染的阳性率分别为56．87％，7．84％，35．29％。其中女性感染率明显高于男性（P〈0．01）。药敏结果显示，支原体对四环素（TET）的敏感性最高，其次是罗红霉素（ROX）；对阿奇霉素（AZI）的耐药率最高。所有阳性样本中，78．43％的菌株有多重耐药现象，且12种抗菌药物都有耐药菌株出现。结．论该院支原体的感染检出率很高，尤其要关注Uu和Uu＋Mh的感染。因此加强支原体培养和药敏试验，对指导临床用药、最大限度地控制耐药菌株的产生，尤为重要。

Objective Detection of mycoplasma and analysis of drug resistance in the patients of urinary and reproductive system in the local area.Methods Zhuhai Hema Bio-tech company provide us to culture and test the drug sensitivity of mycoplasma. Results Totally 103 patients were collected ,cultured and tested for drug sensitivity. From them there were 51 patients who had mycoplasma（49.51%）.The simple infection of Ureaplasma urealyticum was 29 cases（56.87%） and that of Mycoplasma hominis was 4 cases（7.84%）.The mixed was 18 cases（35.29%）.The rate of infection with the female was more higher than the male. The re- sult of drug sensitivity showed that sensitivity of Mycoplasma to TET was the highest , then was to ROX.AZI was with the high- ested drug resistance.From all of the positive specimens,there 40 cases （78.43%） have multi-resistance.Conclusion The infection rate of Mycoplasma in the patients is in a rising tendency in my hospital. It is important to culture and test the drug sensitivity of Mycoplasma.To control the Myeoplasma infection and supervision management of antibiotics is a urged and important task for us.