期刊文献+

威伐光治疗术后慢性疼痛24例疗效观察 被引量:1

下载PDF
导出
摘要 目的观察威伐光联合加巴喷丁和曲马多治疗慢性术后疼痛(CPSP)的临床疗效。方法将48例CPSP患者随机分为A.B两组,各24例。A组口服加巴喷丁和曲马多治疗,B组在此基础上,辅以威伐光照射治疗,观察并记录两组患者于治疗前(T0)、治疗1周(T1)、治疗2周(T2)、治疗4周(T3)4个时点临床效果及不良反应。结果两组患者在治疗后VAS评分均有所下降(P〈0.05):B组在T1,T2,T3时点的VAS评分下降程度均低于A组(P〈0.05)。两组疼痛缓解有效率在T3时点无差异(P〉0.05):B组显效率优于A组(P〈0.05)。两组睡眠质量评分在治疗后均有所增加(P〈0.05);A组评分在,T2,T3时点较前一时点无增加趋势.B组则随治疗时间延长呈增长趋势。两组未见明显不良反应。结论威伐光联合加巴喷丁和曲马多治疗CPSP安全有效。 Objective To observe the clinical efficacy of water-filtered infrared A (wIRA) irradiation in the treatment of Chronic post-surgical painsyndrome (CPSP).nethods According to complete random design,48 patients with CPSP were divided into two groups:A (n=24)group ,B (n=24) group.the two groups were treated with gabapentin and tramadol and the B group was treated additionally with wlRA irradiation simultaneously. The efficacy and adverse reactions of pretreatment (TO) and 1 week(T1), 2 weeks (T2),4 weeks (T3) after treatment between the two groups were observed an recorded.Results The visual analogue scores (VAS) of two goups after the treatm had declined (P〈0.05);Compared with the A group,VAS of B group were declined more significantly at T1 ,T2,T3 points.Two groups had no statistically significant difference on the effective rate of pain relieve,but- significant efficiency rate of B group was higher than A group (P〈0.05).The quality of sleep cores of two groups had been in- creased (P〈0.05);Compared with previous point,scores had no increased at T2 and T3 points,while B group had increased with the extension of treatment(P〈 0.05).The adverse reactions of two groups had no significant difference(P〉 0.05).Conclusion wIRA irradiation combined with gabapentin and tramado is safe and effective in the treatment of CPSP.
出处 《中国药业》 CAS 2015年第B12期246-247,共2页 China Pharmaceuticals
基金 江苏大学附属医院科技项目课题,项目编号:jdfyRC-2013024 江苏大学临床医学科技发展基金,项目编号:JLY20080025.
关键词 威伐光 慢性术后疼痛 神经病理性疼痛 wIRA CPSP Neuropathic pain
  • 相关文献

参考文献11

  • 1Hinrichs-Rocker A, Schulz K, Jarvinen I, et al.Psychosocial predictors and correlates for chronic post-surgical pain (CPSP)-A systematic review[J].Eur J Pain ,2009,13 (7) :719-730.
  • 2张挺杰.术后慢性疼痛的药物治疗[J].临床药物治疗杂志,2012,10(4):22-24. 被引量:4
  • 3Rashiq S, Dick BD.Post-surgiealpain syndromes : a review for the non- pain specialist [ J ].Can J Anaesth, 2014,61 (2) : 123 - 130.
  • 4纪春梅,李淑丽,马玲,孙德海,姜长林.威伐光照射结合关节腔注射玻璃酸钠治疗膝关节炎[J].世界最新医学信息文摘,2013,13(18):89-90. 被引量:25
  • 5Deumens R,Steyaert A,Schubert M,et al.Prevention of chronic postoperative pain: Cellular,molecular,and clinical insights for mechanism-based treatment approaches[J ].Prog Neurobio1,2013,104: 1-37.
  • 6de Brito Cancado TO, Omais M ,Ashamwi HA ,et al.Chronic Pain after Cesarean Section.Influence of Anesthetic/Surgical Technique and Postoperative Analgesia [ J ].Rev Bras Anestesiol, 2012,62 ( 6 ) : 762-74.
  • 7王家双.慢性手术后疼痛综合征[J].中国疼痛学杂志,2007,13(S):7-8.
  • 8薛照静,黄宇光,赵晶,虞雪融.慢性术后疼痛研究进展[J].中国疼痛医学杂志,2013,19(11):685-689. 被引量:29
  • 9Tobias J,Anniika H, Helmut P, et al.Effects of water-filtered infrared A irradiation on human fibroblasts [J].Free Radic Biol Med, 2010,48 (1) : 153-160.
  • 10Helmut P ,Wolfgang P ,Wemer M ,et al.Effects of water-filered-A and of heat on cell death, inflammation, antioxidative potential and of free radical formation in viable skin-first result [J ].J Photoehem Photobiol, 2014, 138 : 347-354.

二级参考文献40

  • 1刘坚基,刘宝珍,李铁锋.玻璃酸钠关节腔内注射治疗膝关节骨性关节炎的疗效观察[J].临床医药实践,2006,15(5):350-351. 被引量:16
  • 2吴在德,吴肇汉.外科学[M].人民卫生出版社,2007:140.
  • 3赵辨.临床皮肤病学[M].4 版.南京:江苏科技出版社,2010:428-429.
  • 4Ragab A, Deshazo RD. Management of back pain in patients with previous back surgery [J ] . AmJ Med, 2008, 121:272-278..
  • 5Boswell MV, Trescot AM, Datta S, et al. Interventional techniques: evidence- based practice guidelines in the management of chronic spinal pain [ J ] . Pain Physician, 2007, 10:7-111.
  • 6Brandsborg B, Nikolajsen L, Hansen CT, et al. Risk factors for chronic pain after hysterectomy: a nationwide questionnaire and database study [ J ] . Anesthesiology, 2007, 106:1003-1012.
  • 7Wildgaard K, Ravn J, Kehlet H. Chronic post-thoracotomy pain: a critical review of pathogenic mechanisms and strategies for prevention [ J ] . Eur J Cardiothorac Surg, 2009, 36:170-180.
  • 8Steegers MAH, Snik DM, Verhagen AF, et al. Only half of the chronic pain after thoracic surgery shows a neuropathic component [ J ] . J Pain, 2008, 9:955-961.
  • 9Vadivelu N, Schreck M, Lopez J, et al. Pain after mastectomy and breast reconstruction [ J ] . Am Surg, 2008, 74:285-296.
  • 10Nienhuijs S, Staal E, Strobbe L, et al. Chronic pain after mesh repair of inguinal hernia: a systematic review [ J ] . Am J Surg, 2007, 194:394-400.

共引文献67

同被引文献9

引证文献1

二级引证文献7

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部