摘要哮喘是一种慢性气道炎症性疾病,近几十年来哮喘的发病率在不断增加。2014年全球哮喘防治创议组织(global initiative for asthma,GINA)指南指出全世界至少有3亿哮喘患者[1]。世界卫生组织研究统计,每年有约三十万人死于哮喘[2]。国内流行病学资料显示,很多地区儿童哮喘患病率有逐年上升趋势[3]。因此,
1Global Initiative for Asthma(GINA).Global Strategy for Asthma Management and Prevention[EB/OL].http://www.ginasthma.org/ documents/4.
2LOZANO R,NAGHAVI M,FOREMAN K,et al.Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010:a systematic analysis for the Global Burden of Disease Study 2010[J].Lancet,2012,15,380(9859):2095-2128.
4JUNIPER E F,BYRNE P M,GUYATT G H,et al.Development and validation of a questionnaire to measure asthma control[J].European respiratory journal,1999,14(4):902-907.
5SKINNER E A,DIETTE G B,ALGATT-BERGSTROM P J,et al.The Asthma Therapy Assessment Questionnaire(ATAQ)for children and adolescents[J].Dis Manag,2004,7(4);305-313.
6NATHA R A,SORKNESS C A,KOSINSKI M,et al.Development of the asthma control test:a survey for assessing asthma control[J].Journal of allergy and clinical immunology,2004,113(1):59-65.
7PIACENTINI G L,PERONI D G,BODINI A,et al.Childhood Asthma Control Test and airway inflammation evaluation in asthmatic children[J].Allergy,2009,64(12);1753-1757.
8ELIZABETH C,SUZANNA S,TIM C F,et al.Pediatric asthma quality of life questionnaire:validation in children from Singapore [J].Asian Pac J Allergy Immunol,1999,17(3):155-161.
9GANDHI P K,KENZIK K M,THOMPSON L A,et al.Exploring factors influencing asthma control and asthma-specific health-related quality of life among children[J].Respir Res,2013,14:26-36.
5Dietz WH, Robinson TN. Use of the body mass index (BMI) as a measure of overweight in children and adolescents. J Pediatr, 1998, 132 : 191-193.
6Cole TJ, Bellizzi MC, Flegal KM, et al. Establishing a standard definition for child overweight and obesity worldwide : international. survey. BMJ, 2000, 320: 1240-1243.
7Cole TJ, Freeman JV, Preece MA. Body mass index reference curves for UK, 1990. Arch Dis Child, 1995, 73 : 25-29.
8Ogden CL, Kuczmarski R J, Flegal KM, et al. Centers for Disease Control and Prevention 2000 growth charts for the United States: improvements to the 1977 National Center for Health Statistics version. Pediatric, 2002, 109:45-60.
9Cole TJ, Roede MJ. Centiles of body mass index for Dutch children aged 0-20 years in 1980 - a baseline to assess recent trends in obesity. Ann Hum Biol, 1999, 26:303-308.
10Inokuchi M, Hasegawa T, Anzo M, et al. Standardized centile curves of body mass index for Japanese children and adolescents based on the 1978-1981 national survey data. Ann Hum Biol, 2006, 33: 444-453.