卵巢早衰相关因素分析

目的探讨影响卵巢早衰的危险因素及保护因素,为卵巢早衰的预防提供科学依据。方法选取确诊的卵巢早衰(premature ovarian failure,POF)女性60例为研究组,同时选取月经规则、性激素检查在正常范围内的、年龄匹配的卵巢功能正常的女性60名为对照组,分别填写自制《POF相关因素调查问卷表》,对调查结果进行比较,并采用单因素、多因素Logistic回归法进行分析。结果 POF的危险因素有盆腔手术史、腮腺炎史、染发、小事烦恼、疲倦、压抑及压力大;保护因素为经常食用水果蔬菜与豆制品。结论养成良好的生活习惯,多食水果蔬菜及豆制品,不染发,远离有毒物质,及时预防接种,学会调整及缓解压力,减少负面情绪,保持心理健康有利于维持正常的卵巢功能。

Objective To investigate the risk and protective factors of POF, to provide scientific basis for the prevention of POF. Methods 60 cases POF women selected as the study group, at the same time, 60 cases normal woemen selected for menstruation rule, serum sex hormone in the normal range, age matched and ovarian function normal as the control group. They filled in self-made related factors of POF questionnaire respectively. We compared the survey results and used single factor and multiple factors logistic regression analysis. Results The risk factors of POF were pelvic operation history, mumps history, hair coloring, small troubles,fatigue, depression and stress; protective factors of POF were often eating fruits and vegetables and soy products. Conclusion Developing good living habits, eating more fruits and vegetables and soy products, not hair coloring, staying away from toxic substances, timely vaccination, learning to adjust and ease the pressure, reducing the negative emotions, maintaining mental health are conducive to the maintenance of normal ovarian function.