摘要
目的探讨急性缺血性脑卒中患者血清胱抑素C水平与脑白质病变（WMLs）的相关性。方法符合诊断标准的缺血性脑卒中患者105例,根据Fazekas量表评估WMLs严重程度分为无或轻度WMLs组和重度WMLs组,比较两组相关资料的差异,分析重度WMLs的危险因素。结果两组年龄、高血压和胱抑素C水平存在统计学差异（P〈0.05）。年龄（OR=1.06,95%CI=1.01-1.12,P〈0.05）和胱抑素C水平（OR=1.32,95%CI=1.07-1.55,P〈0.01）是急性缺血性脑卒中患者伴发重度WMLs的独立危险因素。结论年龄和胱抑素C水平是急性缺血性脑卒中患者伴发重度WMLs的独立危险因素。
Objective To investigate the correlation between serum cystatin C and white matter lesions（WMLs）in the patients with cerebral ischemic stroke.Methods On the basis of Fazekas scores,105 patients with cerebral ischemic stroke were assigned into two groups of A（without or with mild WMLs,63 cases）and B（with severe WMLs,42 cases）.Clinical data were compared between two groups and the risk factors related to WMLs were analyzed.Results The differences in age,hypertension and cystatin C between two groups were significant（P〈0.05）.The age（OR=1.06,95%CI=1.01-1.12,P〈0.05）and cystatin C（OR=1.32,95%CI=1.07-1.55,P〈0.01）were the independent risk factors for severe WMLs.Conclusion The age and cystatin C level are the independent risk factors for severe WMLs in the patients with cerebral ischemic stroke.
出处
《江苏医药》
CAS
2016年第4期414-416,共3页
Jiangsu Medical Journal
关键词
胱抑素C
缺血性卒中
脑白质病变
Cystatin C
Cerebral ischemic stroke
White matter lesions
