胃癌与凝血功能的研究进展

Progress of gastric cancer and coagulation function

胃癌与凝血功能之间存在着密切的关系.一方面,胃癌导致患者凝血、抗凝及纤溶等凝血机制发生改变,从而引发高凝状态及血栓性相关疾病;另一方面,患者凝血功能的异常进一步加速了胃癌的进展,严重影响患者的预后.笔者对国内外关于胃癌与凝血功能的相关研究进行了综述,以引起临床医师对胃癌凝血功能异常及抗凝治疗的重视.

The gastric cancer is closely related to the coagulation function.On the one hand,gastric cancer result in changes of coagulation mechanism such as blood coagulation,anticoagulation and fibrinolysis coagulation,which further result in hypercoagulable state and thrombosis related diseases.On the other hand,the abnormal of the coagulation function aggravate the progress of stomach cancer,and affect the prognosis of patients seriously.We review the domestic and international studies on the relationships between gastric cancer and coagulation function,and clinical doctors should pay attention to the abnormal of coagulation function and anticoagulaion treatment on gastric cancer.