摘要
目的探究根治术与保乳术联合术后放疗治疗早期乳腺癌的疗效对比。方法研究对象选取2008年1月~2011年1月之间我院收治的112例Ⅰ期、Ⅱ期乳腺癌患者,根据手术方式不同分为根治术组71例和保乳术组41例,根治术组患者采用改良根治术治疗,保乳术组患者实施保乳手术并术后给予全乳适形调强放疗,两组术后均采用CEF方案进行化疗,对比两组患者的3年生存率、远端转移、局部复发情况。结果根治术组患者的3年生存率为94.4%(67/71),远端转移率为4.2%(3/71),局部复发率为7.0%(5/71);保乳术组患者的3年生存率为90.2%(37/41),远端转移率为9.8%(4/41),局部复发率为7.3%(3/41),两组患者的3年生存率和局部复发率对比无显著差异,但保乳术组患者的远端转移率显著高于根治术组患者(P〈0.05)。结论保乳手术联合术后放疗相较于根治术而言,对乳腺癌患者术后的影响较小,且3年生存率、局部复发情况与根治术相近,但远端转移率较高,可根据情况进行选择。
Objectives To explore the effect of radical mastectomy combined with breast conserving surgery in the treatment of early breast cancer. Methods 112 patients with Ⅰ and Ⅱ were selected from 2008. 1 -2011.1,41 cases of breast cancer, 71 ca- ses of breast conserving surgery, eases of breast conserving surgery and postoperative radiotherapy. The two groups were treated with CEF. The 3 year survival rate, distant metastasis and local recurrence were compared between the two groups. Results The 3 year survival rate was 94.4% (67/71), 4. 2% (3/71), 7% years survival rate was 9.8% (37/41), 7. 3% (4/41), 3 years survival rate and local recurrence rate in two groups were significantly higher than those in radical operation group ( P 〈 0. 05 ). Conclusions The effect of breast conserving surgery'combined with postoperative radiotherapy is small, and the 3 year survival rate and local recurrence rate are similar, but the distal metastasis rate is higher, and can be chosen according to the situation.
出处
《中国老年保健医学》
2016年第1期99-100,共2页
Chinese Journal of Geriatric Care
关键词
早期乳腺癌
改良根治术
保乳手术
术后放疗
early breast cancer, modified radical mastectomy, breast conserving surgery, postoperative radiotherapy