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吗替麦考酚酯与泼尼松联合用药治疗小儿紫癜性肾炎的临床疗效观察 被引量:9

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摘要 目的分析吗替麦考酚酯与泼尼松联合用药治疗小儿紫癜性肾炎的临床疗效。方法 80例小儿紫癜性肾炎患儿,随机分成常规组和试验组,每组40例。常规组患儿应用环磷酰胺冲击+泼尼松,试验组患儿应用吗替麦考酚酯+泼尼松。对比两组患儿治疗效果、治疗前后24 h尿蛋白定量、尿素氮、血清肌酐和血清白蛋白的差异。结果试验组患儿治疗总有效率明显高于常规组(P<0.05)。试验组24 h尿蛋白定量、尿素氮、血清肌酐和血清白蛋白改善程度均明显优于常规组(P<0.05)。结论吗替麦考酚酯与泼尼松联合用药治疗小儿紫癜性肾炎的临床疗效确切,可有效改善患儿肾功能,改善患儿预后,值得推广。
出处 《中国现代药物应用》 2016年第6期136-137,共2页 Chinese Journal of Modern Drug Application
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