摘要
宫颈癌是常见妇女恶性肿瘤。随着早期筛查及手术的广泛应用，宫颈癌发病率逐年下降，但死亡率却无明显降低趋势，患者多死于癌症转移和复发。E-钙黏蛋白（E-cadherin）是细胞间黏附和连接复合体的中心环节，已被大量文献证实与宫颈癌发生发展过程的密切联系。现就E—cadher-in与宫颈癌发生发展的相关研究进行整理，并予以综述。
Cervical cancer is women＇s common malignant tumor. With the extensive application of N screening and early surgery, cervical cancer incidence declines year by year, but no decrease mortality trend. The patient died of cancer metastasis and recurrence. E-cadherin is the central link of intercellular adhesion, and junction complex has been. confirmed by a large number of literature and closely associates cervical cancer development. This review summarizes the relevant research between E-cadherin and the oc- currence and development of cervical cancers.
出处
《中国医师杂志》
CAS
2016年第2期305-307,共3页
Journal of Chinese Physician
基金
湖南省自然科学基金联合项目（14JJ7090）
湖南省科技厅课题（2013FJ3129）
