摘要
目的研究谷氨酰胺防治早产儿喂养不耐受的临床应用。方法抽取2011年2月~2014年2月住院的180例早产儿分为观察组（使用谷氨酰胺组）和对照组,比较两组患儿的免疫指标和NEC的发生率。结果观察组患儿每天排便次数多于对照组,肠外营养时间短于对照组,达到足量肠道喂养时间短于对照组,住院时间短于对照组（P〈0.05）。观察组早产儿喂养不耐受现象的发生天数为（0.73±1.2）d,明显低于对照组的（2.88±2.52）d,观察组院内总感染率为4.4%,低于对照组的20.0%,差异有统计学意义（P〈0.05）。结论早期应用谷氨酰胺能够减少早产儿喂养不耐受现象发生的天数,减少院内感染及NEC的发生率。
Objective To discuss clinical application of Glutamine in prevention and treatment of preterm children feeding intolerance. Methods 180 preterm children from Feb 2011 to Feb 2014 were selected and divided into observation group（treatment of Glutamine） and control group.Immune parameters and the incidence of NEC of two groups were compared. Results The number of daily bowel movements of observation group were less than the control group,parenteral nutrition was shorter than the control group,time of reaching full enteral feeding amount was shorter than the control group, and the hospital stay was shorter than the control group（P 〈 0.05）. Feeding intolerance of observation group continued for（0.73 ± 1.2）d, which was shorter than control group of （ 2.88 ± 2.52 ） d.Nosocomial infection rate of observation was 4.4%, which was lower than control group（20.0%）（P 〈 0.05）. Conclusion Early application of glutamine can shorten continue time of feeding intolerance in preterrn children,and decreasenosocomial infection and NEC rates.
出处
《中国医药科学》
2016年第2期63-65,共3页
China Medicine And Pharmacy
基金
广东省佛山市医学科学技术研究计划课题(2012230)
