青春期异常子宫出血诊治临床探讨

Clinical exploration of diagnosis and treatment of adolescent abnormal uterine bleeding

目的分析青春期异常子宫出血诊治临床方法和效果。方法随机选取2013年6月~2015年6月于本院就诊的71例青春期异常子宫出血患者作为研究对象,随机分组。雌孕激素组患者予以雌孕激素联合治疗,去氧孕烯炔雌醇组患者予以去氧孕烯炔雌醇片治疗;比较两组患者的临床疗效以及用药副作用、出血初步控制时间和出血完全控制时间。结果去氧孕烯炔雌醇组患者的临床总治疗效率明显高于雌孕激素组,其中雌孕激素组总有效率为96.67%,雌孕激素组总有效率为77.42%,差异有统计学意义（P〈0.05）。去氧孕烯炔雌醇组治疗过程用药副作用发生率跟雌孕激素组相似,雌孕激素组发生率为9.68%,去氧孕烯炔雌醇组发生率为10.00%,差异无统计学意义（P〉0.05）。去氧孕烯炔雌醇组患者出血初步控制时间和出血完全控制时间明显短于雌孕激素组,差异无统计学意义（P〉0.05）。结论去氧孕烯炔雌醇片治疗青春期异常子宫出血的临床效果好,可推广应用。

Objective To analyze the clinical methods and effects of the diagnosis and treatment of adolescent abnormal uterine bleeding. Methods 71 patients with adolescent abnormal uterine bleeding who were admitted to our hospital from June 2013 to June 2015 were randomly selected as research objects and they were randomly allocated to the estrogen and progesterone group and the desogestrel ethinylestradiol group.Patients in the estrogen and progesterone group were received combined treatment of estrogen and progesterone while patients in the desogestrel ethinylestradiol group were received treatment of desogestrel ethinylestradiol tablets.Clinical curative effect,side effects of drugs, bleeding preliminary control time and bleeding complete control time of patients in two groups were compared. Results Clinical total effective rate of the desogestrel ethinylestradiol group was 96.67%,significantly higher than that of the estrogen and progesterone group 77.42% （P 〈 0.05）.Incidence of side effects of drugs in treatment of the desogestrel ethinylestradiol group was 10.00%,similar to that of the estrogen and progesterone group 9.68% （P 〉 0.05）.Bleeding preliminary control time and bleeding complete control time of the desogestrel ethinylestradiol group was significantly shorter than that of the estrogen and progesterone group （P 〈 0.05）. Conclusion Desogestrel ethinylestradiol tablet in treatment of adolescent abnormal uterine bleeding has a good clinical effect,worthy of promotion and application.