糖尿病性黄斑病变的频域OCT特点分析

Characters of diabetic maculopathy in frequency-domain optical coherence tomography

目的分析糖尿病性黄斑病变（DM）的频域OCT特点。方法将2014年3月。2015年10月在院的经眼底荧光血管造影（FFA）确诊为糖尿病视网膜病变（DR）的患者35例60只眼，分为非增生期DR（NPDR）组28只眼．增生期DR（PDR）组32只眼。30例健康人30只眼为对照组。回顾性分析其CirrusHD—OCT黄斑容积512×128扫描结果。结果OCT显示DR患者22只眼（36．7％）黄斑区视网膜增厚，27只眼（45．0％）外核层（ONL）／外丛状层（OPL）弥漫性水肿，10只眼（16．7％）内核层（INL）囊样水肿。NPDR组与PDR组9个分区视网膜厚度、总容积和总平均厚度等差异无统计学意义（P〉0．01），均高于对照组（P〈0．01）。结论DM的严重程度与DR分期并不平行。OCT是诊断与治疗DM的必备工具之一。

Objective To study characters of diabetic maculopathy（DR） in frequency-domain OCT. Methods A total of 60 eyes of 35 patients in hospital from March 2014 to October 2015 after the diagnosis of DR by FFA were divided into NPDR group（28 eyes） and PDR group（32 eyes）. 30 eyes of 30 healthy persons were in control group. Characters of them in Cirrus HD-OCT macular volume 512~128 scans were analyzed retrospectively. Results OCT reported that macular retinal thickening was found in 22 eyes（36.7%）, diffuse edema in ONL/OPL in 27 eyes（45.0%）, cystoid ede- ma in INL in 10 eyes（16.7%）. Nine subfield thickness,cube volume and cube average thickness in NPDR and PDR groups had no difference statistically（P〉0.01）, which were larger than that in control group（P〈0.01）. Conclusion The degree of DM had no parallel relation with the classification of DR. OCT was one of necessary tools for diagnosis and remedy DM.