龙葵生物碱提取及检测方法研究进展

Research Progress in Extraction and Detection Methods of Alkaloids from Solanum Nigrum

龙葵为双子叶茄科茄属一年生草本植物,生物碱类化合物是龙葵的主要生物活性成分,具有较强的抗肿瘤活性。目前,龙葵生物碱的提取方法有溶剂提取、超声提取、微波提取、超临界萃取、柱层析等,检测方法有酸性染料比色法、薄层扫描法、高效液相色谱法、反相高效液相色谱法、超高效液相色谱法等。本文对近年来龙葵生物碱提取及检测方法的研究进展进行综述,旨在为龙葵碱的研究和开发提供参考。

Solanum Nigrum is a kind of dicotyledon solanaceae annual herb, and alkaloids are its main bioactive constituents, with good antitumor activity. The current extraction methods for alkaloids include solvent extraction, ultrasonic extraction, microwave extraction, supercritical fluid extraction, and column chromatography etc, while the detection methods include acid dye colorimetry, thin layer scanning, high performance liquid chromatography, reversed-phase high performance liquid chromatography, and ultra-high performance liquid chromatography etc. This article reviewed the research progress in extraction and detection methods of alkaloid from Solanum Nigrum in recent years, so as to provide references for further research and development of alkaloid from Solanum Nigrum.