脑干急性梗死弥散加权成像的相关性分析研究

Incidence of brainstem acute infarction on diffusion-weighted imaging

目的应用弥散加权成像（DWI）探讨脑干急性梗死的发生率及其与年龄、性别的相关性。方法对连续8 063例行头颅MRI和DWI检查的患者资料进行回顾性分析,年龄1~98岁,平均62岁。按性别及年龄进行分组,观察脑干急性梗死的发生率并进行统计分析。结果 8 063例中,脑干急性梗死175例,发生率为2.17%,〈20岁、20~39岁、40~59岁、60~79岁和≥80岁年龄组脑干急性梗死的发生率依次为0（0/552）、0.70%（4/568）、1.99%（59/2 966）、2.61%（91/3 484）和4.26%（21/493）。脑干急性梗死男、女发生率分别为2.87%（120/4 177）和1.42%（55/3 886）,性别间差异有统计学意义（χ2=20.142,P=0.000）。结论脑干急性梗死的总体发生率为2.17%,随年龄增长发病率呈上升趋势,男性多见。

Objective To explore the incidence of brainstem acute infarction using diffusionweighted imaging（DWI） and its correlation with age and gender. Methods Brain MR images of 8 063 consecutive patients（age range, 1-98 years; mean age, 62 years） were analyzed retrospectively. Incidence of brainstem acute infarction in different sex and age groups were recorded and statistically analyzed. Results Brainstem acute infarction were found in 175 of 8 063 patients, the total incidence of brainstem acute infarction was 2.17%. The incidence of brainstem acute infarction for groups of age 20, 20-39, 40-59, 60-79 and ≥80 years old was 0%（0/552）, 0.70%（4/568）, 1.99%（59/2 966）, 2.61%（91/3 484） and 4.26%（21/493）, respectively. The incidence of brainstem acute infarction for male and female were 2.87%（120/4 177） and 1.42%（55/3 886）（χ2=20.142, P=0.000）, respectively. Conclusion The total incidence of brainstem acute infarction was 2.17%, which increased with age. The incidence of brainstem acute infarction was higher in males than in females.