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我院主要病原菌分布及耐药性分析

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摘要 目的探讨我院住院及门诊患者主要致病菌的分布及耐药性,为感染患者的治疗提供依据.方法:选取2012年 01月-2015年09月住院及门诊患者20587例,收集所有患者的合格临床标本分离出9571株致病菌,采用法国生物梅里埃VITEK-2 Compack全自动微生物仪对病原菌进行鉴定及药物敏感试验,使用WHONET5.6软件进行统计分析.结果:患者标本中共培养出致病菌9571株,居于前5位的依次为:铜绿假单胞菌、大肠埃希菌、鲍曼不动杆菌、肺炎克雷伯菌、嗜麦芽窄食单胞菌;分别占致病菌总数的13.75 %、13.42 %、10.47 %、6.96 %、4.56%;铜绿假单胞菌的耐药率依次为:阿米卡星4.85%、哌拉西林他唑巴坦15.32%、妥布霉素19.75%、庆大霉素20.47%、左氧氟沙星24.68%、哌拉新林27.85%、头孢他啶28.16%、头孢吡肟30.16%;亚胺培南、美罗培南耐药性高,分别为51.62%、54.14%;大肠埃希菌对亚胺培南、美罗培南高度敏感,耐药率为0,头孢替坦耐药率低,为3.06%,ESBLs菌株占63.62%.结论:我院主要致病菌以铜绿假单胞菌、大肠埃希菌、鲍氏不动杆菌、肺炎克雷伯菌、嗜麦芽窄食单胞菌为主;铜绿假单胞菌居第一位,亚胺培南、美罗培南耐药性高达51.62%、54.14%;大肠埃希菌对亚胺培南、美罗培南、头孢替坦高度敏感,ESBLs菌株占63.62%.临床医生应根据药敏选择药物以减少耐药菌株的产生.
出处 《世界中医药》 CAS 2015年第A02期1654-1655,共2页 World Chinese Medicine
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