名老中医治疗风湿性心脏病用药Varclus聚类分析

Varclus Cluster Analysis on Proven Cases Record of Treating Rheumatic Heart Disease by Famous Veteran Teran Doctors of TCM

目的:对名老中医治疗风湿性心脏病用药进行聚类分析,挖掘其用药经验。方法:将名老中医治疗风湿性心脏病的125份病例录入验案分析系统,建立频率统计表,导出数据,利用SAS软件的Varclus功能,对频率>10%的34味中药进行聚类分析。结果:34味中药分为9类:1白芍、白术、当归、阿胶、桂枝、红花、黄芪、熟地、赤芍;2焦麦芽、鸡内金、焦神曲;3车前子、葶苈子、猪苓;4附子、川芎、人参、炙甘草;5麦冬、沙参、太子参、玉竹、生地;6半夏、大枣、生姜;7五味子、远志;8茯苓、泽泻;9益母草、丹参、桃仁。结论:名老中医在治疗不同证型风湿性心脏病时,常选用特定的配伍组合,值得临床学习应用。

Objective ： To analyze the rule of using Chinese medicine of famous veteran reran doctors of TCM in treating？ rheumatic heart disease, by the way of Varclus analysis. Methods：Input the 125 proven cases record of famous veteran teran doctors to the a nalysis software of proven cases, and export data to SAS software, then make the Varclus regression analysis of the 34 kinds of drugs which frequency is more than 10 %. Results：These 34 kinds of drugs is divided into 9 categories：@radices paeoniae alba, bighead atractylodes rhizome, Angelica sinensis, colla corii asini, cassia twig, safflower carthamus, Astragalus membranaceus, Rehmannia Glutinosa, Radix Paeoniae Rubra; （2）coking malt, endothelium corneum gigeriae galli, scorch-fried medicated leaven; （3）Plan rain Seed, Pepperweed Seed, Polyporus umbellatus, （4）Aconitum earmichaelii, Ligusticum wallichii, Ginseng, Radix Glycyrrhizae Preparata; （5）Ophiopogon j aponicus, Radix Adenophorae, radix pseudostellariae, radix polygonati officinalis, Rhizome of rehmannia, （6） Pinellia ternata, （7） Fructus Ziziphi Jujuhae, Ginger;（8）Poria cocos, rhizoma alismatis, （9）motherwort, the root of red rooted salvia, peach kernel. Conclusion：When the Famous Veteran Teran Doctors of TCM treating rheumatic heart disease, they will select some specific drugs as groups, which are worthy of study.