阻塞性睡眠呼吸暂停低通气综合征与心血管事件被引量：15

Obstructive sleep apnea hyponea syndrome and cardiovascular event

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摘要随着"睡眠债"的出现及积累,阻塞性睡眠呼吸暂停低通气综合征崭露头角,并引起人们的关注。尽管它暂未纳入心血管风险评估中,但因它可引起或促进一系列心血管事件,已成为心血管死亡的预测器。其致心血管事件的主要病理生理机制涉及间歇性低氧血症和复氧、交感神经系统的激活、胸腔内压力的变化等。 With the appearance and accumulation of ＂sleep debt＂,obstructive sleep apnea hypopnea syndrome began to emerge,and has attracted people＇s attattention.While the syndrome is not yet integrated in the assessment of cardiovascular risk,it has become a predictor of cardiovascular mortality for the causation or promotion of cardiovascular events.The leading pathophysiological mechanisms is strongly related to intermittent hypoxemia and re-oxygenation,stimulation of the sympathetic nervous system,changes in intrathoracic pressure,and so on.

作者刘伶俐苏晓灵

机构地区青海大学医学院青海省人民医院心内科

出处《临床心血管病杂志》 CAS CSCD 北大核心 2016年第2期116-118,共3页 Journal of Clinical Cardiology

基金青海省科学技术厅(应用)基础研究计划项目(No:2014-ZJ-741)

关键词慢性间歇性缺氧交感神经持续正压通气 chronic intermittent hypoxia sympathetic nervous system continuous positive airway pressure

分类号 R544.1 [医药卫生—心血管疾病]

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