病毒在哮喘发作的研究进展

Research progress of virus infection in the asthma exacerbation

哮喘的本质是气道的炎性反应,规律吸入糖皮质激素和β2受体激动剂可控制哮喘,但在此治疗基础上呼吸道病毒感染仍可导致哮喘的发作。固有及适应性免疫缺陷削弱抗病毒反应,而过敏性炎性反应有协同作用。随着对其机制的深入了解,为开辟新的防治提供新思路。

The airway inflammation is the nature of asthma. Although symptoms can be well controlled by corticosteroids and β2-agonists,viral respiratory tract infections can still cause exacerbations. The defect of inherent and adaptive immunity impaired the the antiviral response,with the synergetic effect of allergic inflammatory reaction.The better understanding of the mechanism will provide new prevention and treatment of the disease.