不同部位胃溃疡Hp根治术疗效研究

Study on the therapeutic effect of Helicobacter Pylori Eradication to gastrohelcosis on different location

目的:研究不同部位胃溃疡Hp根治术的疗效。方法:收集胃底溃疡患者(FU)42例、胃体溃疡患者(CU)76例及胃窦部溃疡患者(AU)260例,给予Hp根治术,观察术后根治率及复发率。结果:FU、CU、AU的Hp根治率分别为90.4%、85.6%、76.5%,差异有统计学意义(P<0.05)。6个月后Hp复发率,FU、CU、AU分别为7.8%、13.8%、28.6%,差异有显著统计学意义(P<0.01)。结论:Hp根治术疗效与溃疡部位有关,其中胃窦部根治率最低,复发率最高,或是溃疡及癌症好发原因之一。

Objective： To investigate the therapeutic effect of Helicobacter Pylori eradication on gastrohelcosis on different location.Methods：the radical rate and recurrence rate of 42 patients with gastric fundus ulcer（FU）, 76 patients with gastric corporeal ulcer（CU） and 260 patients with gastric Antrum ulcer（AU） after being treated with Hp eradication were collected and analyzed.Results：The radical rates of CU, AU, FU were 90.4%, 85.6% and 76.5% respectively and the difference was of statistically significant（P0.05）, the recurrence rates after 6 months of CU, AU,FU patients were 7.8%, 13.8% and 28.6% respectively, and the difference was statistically significant（P0.01）. Conclusion：The therapeutic effect of HP eradication was correlated the location of gastrohelcosis. Among them, the radical rate of gastrohelcosis was of lowest radical rate and highest recurrence rate, which may be a contributing factor for high occurrence rate of the ulcer and cancer.