急性心肌梗死患者入院后CRP及WBC水平与住院期间死亡的相关性研究

Correlation of CRP and WBC Content with Risk of Death in AMI Patients Admitted to Hospital

目的：探讨急性心肌梗死（Acute Myocardial Infarction,AMI）患者入院后C反应蛋白（C-reactive protein,CRP）及白细胞（WBC）水平与住院期间死亡的相关性。方法：选择2008年1月至2013年1月我院收住的AMI患者共281例,对所有AMI患者的临床资料及实验室检查等进行统计分析。采用Logistic回归分析CRP、WBC水平与患者住院期间死亡的关系。结果：Logistic回归分析显示,随着CRP与WBC水平的升高,AMI患者的死亡率亦呈现逐渐升高的趋势（P〈0.05）;以CRP与WBC最低分位作为参比,最高分位的患者发生死亡的OR值（95%CI）分别为1.80（0.90-3.58）、4.47（2.12-9.40）。结论：CRP及WBC水平的上升与AMI患者住院期间死亡的危险性具有密切相关性。

Objective： To study the correlation of CRP and WBC content with risk of death in AMI patients admitted to hospital. Method： 281 AMI patients treated from January 2008 to January 2013 in our hospital were selected. The clinical data and laboratory examination data were analyzed. By logistic regression analysis,the correlation of CRP and WBC content with risks of death was investigated. Result： The death rate of AMI patients gradually increased with the higher CRP and WBC content（ P〈 0. 05）; based on the reference of lowest marks of CRP and WBC contents,OR value（ 95% CI） in patients with highest marks was1. 80（ 0. 90 - 3. 58） and 4. 47（ 2. 12 - 9. 40）. Conclusion： The increasing CRP and WBC content has a close relationship with the risk of death in AMI patients upon being admitted to hospital.