急性冠脉综合征患者降钙素原水平和血管内超声特点的关系被引量：4

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摘要目的观察急性冠脉综合征患者降钙素原(PCT)水平和血管内超声(IVUS)特点的关系。方法选择急性冠脉综合征(ACS)患者14例,稳定型心绞痛(SAP)患者16例,冠脉造影结果正常的患者30例为正常对照组。运用全自动电化学发光免疫分析仪定量测定检测PCT浓度、冠脉造影术(CAG)及IVUS评价冠脉斑块的形态特征。结果 3组间PCT水平比较有统计学差异。SAP及正常对照组血清PCT水平低于ACS组(P<0.01),正常对照组PCT水平低于SAP组(P<0.01)。血清PCT水平与软斑块面积百分比(r=0.358,P=0.011)、偏心指数(r=0.458,P=0.007)、血管重构指数(r=0.421,P<0.001)呈正相关。结论 ACS组PCT水平高于SAP组和对照组,PCT水平与IVUS评价易损性指标相关,可作为易损斑块的炎症标记。

作者乔锐朱贤光项学军辜和平宋德明

机构地区安徽医科大学附属安庆医院安庆市立医院心内科

出处《中国老年学杂志》 CAS CSCD 北大核心 2016年第5期1100-1102,共3页 Chinese Journal of Gerontology

关键词急性冠脉综合征易损斑块降钙素原血管内超声

分类号 R541.4 [医药卫生—心血管疾病]

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参考文献18

1Manoharan G,Ntalianis A,Muller O,et al.Severity of coronary arterial stenoses responsible for acute coronary syndromes[J].Am J Cardiol,2009;103(9):1183-8.
2Topol EJ,Teirstein PS.Textbook of interventional cardiology[M].7thed Canada:Elsevier,2015:117-31.
3Sinclair H,Bourantas C,Bagnall A et al.Oct for the identification of vulnerable plaque in acute coronary syndrome[J].JACC Cardiovasc Imaging,2015;8(2):198-209.
4Xie Y,Mintz GS,Yang J,et al.Clinical outcome of nonculprit plaque ruptures in patients with acute coronary syndrome in the prospect study[J]JACC Cardiovasc Imaging,2014;7(4):397-405.
5Braunwald E.Progress in the noninvasive detection of high-risk coronary plaques[J].J Am Coll Cardiol,2015;66(4):347-9.
6刘健,徐迎佳,王伟民,刘传芬,卢明瑜,马玉良.冠状动脉造影显示的模糊病变的血管内超声价值[J].中国循环杂志,2009,24(6):425-428. 被引量：6
7Mintz GS,Nissen SE,Anderson WD,et al.American college of cardiology clinical expert consensus document on standards for acquisition,measurement and reporting of intravascular ultrasound studies(ivus).A report o the american college of cardiology task force on clinical expert consensus documents[J].J Am Coll Cardiol,2001;37(15):1478-92.
8Hong MK,Mintz GS,Lee CW,et al.Comparison of coronary plaque rupture between stable angina and acute myocardial infarction:A three-vesse intravascular ultrasound study in 235 patients[J].Circulation,2004;110(8):928-33.
9Nicholls SJ,Sipahi I.Emerging role of intravascular ultrasound in the assessment of experimental anti-atherosclerotic therapies[J].Curr Med Chem,2006;13(15):1727-34.
10Assicot M,Gendrel D,Carsin H,et al.High serum procalcitonin concentrations in patients with sepsis and infection[J].Lancet,1993;341(8844):515-8.

二级参考文献25

1王丽凤,郑延松,刘文艳.D-二聚体与急性冠脉综合征[J].临床内科杂志,2006,23(5):359-360. 被引量：13
2Abizaid AC, Piegas KS, Abizaid AA, et al. The use of intravascular ultrasound in deciding on the treatment of moderate coronary lesions. Arq Bras Cardiol 2004,83:3-6.
3Shigeru N, Donald JM, Bavani M, et al. An explanation for discrepancy between angiographic and intravascular ultrasound measurement after percutaneous transluminal coronary angioplasty. J Am Coil Cardiol 1995,25:633-639.
4Mintz GS, Nissen SE, Anderson WD, et al. American College of Cardiology clinical expert consensus document on standards for acquisition, measurement and reporting of intravascular ultrasound studies (IVUS) :a report of the American College of Cardiology Task Force on Clinical Expert Consensus Documents. J Am Coll Cardiol 2001,37 : 1478-1492.
5Mottram PM, Meredith IT. Intravascular ultrasound assessment of ambiguous coronary lesions. Heart, Lung and Circulation, 2001,10 : 58- 62.
6Ken K, Kinji I. Haziness on coronary angiogram after percutaneous transluminal coronary angioplasty evaluated with angioscopy. Angiology,2002,53 : 171-176.
7Leesar MA, Masden R, Jasti V. Physiological and intravaseular ultrasound assessment of an ambiguous left main coronary artery stenosis. Catheter Cardiovasc Interv ,2004,62:349-357.
8Ricciardi M J, Meyers S, Choi K, Pang JL, Goodreau L, Davidson CJ. Angiographically silent left main disease detected by intravascular ultrasound:a marker for future adverse cardiac events. Am Heart J 2003,146:507-512.
9Okabe T, Weigold WG, Mintz GS, et al. Comparison of intravascular ultrasound to contrast-enhanced 64-slice computed tomography to assess the significance of angiographically ambiguous coronary narrowings. Am J Cardiol,2008 ,102 :994-1001.
10Okabe T, Weigold WG, Mintz GS, et al. Comparison of Intravascular Ultrasound to Contrast-Enhanced 64-Slice Computed Tomography to Assess the Significance of Angiographic Ambiguous Coronary Narrowings. Am J Cardiol,2008,102:994-1001.