保乳手术与改良根治术治疗早期乳腺癌的临床效果对比分析

Comparative analysis of clinical effect of breast conserving surgery and modified radical operation for early breast cancer

目的:探讨早期乳腺癌患者运用保乳手术及改良根治手术治疗的临床价值.方法:选取2011-10/2014-02新疆克拉玛依市独山子人民医院收治的68例早期乳腺癌患者作为研究对象,并随机分为对照组(n=34)和观察组(n=34).对照组接受改良根治术治疗,观察组行保乳手术治疗,对比两组手术具体处理情况,包括手术操作时间、术中出血量、切口大小、平均住院时间、美容效果及术后1年的复发率等.结果:经手术治疗,观察组的手术操作时间、平均住院天数、术中出血量明显少于对照组,且切口明显小于对照组,差异具有统计学意义(P<0.05);观察组的美容优良率占94.1%,明显高于对照组的79.4%,差异具有统计学意义(P<0.05);观察组术后1年复发率占2.9%,与对照组的2.9%比较,差异无统计学意义(P>0.05).结论:对早期乳腺癌患者行保乳手术治疗,效果较改良根治术更为理想,且可保证美观性,术后复发率低,值得应用推广.

AIM： To investigate the clinical value of breast conserving surgery and modified radical operation for early breast cancer. METHODS： A total of 68 patients with early breast cancer from October 2011 to February 2014 were selected as. research objects and randomly divided into the control group（ n = 34） and the observation group（ n = 34）. The former was given modified radical operation,and the latter was given breast conserving surgery. The operation time,bleeding volume during operation,size of the incision,average hospitalization time,cosmetic result and recurrence rate of 1 year after operation were compared. RESULTS： The operation time,average hospitalization time,bleeding volume during operation and the size of the incisionin the observation group were significantly less than those of the control group,and the differences were statistically significant（ P〈0. 05）; The excellent rate of beauty was 94. 1% in the observation group,which was significantly higher than the control group（ 79. 4%）,and the difference was statistically significant（ P 0. 05）; There was no statistically significant difference in the recurrence rate of of 1 year after operation between observation group（ 2. 9%） and control group（ 2.9%）（ P 0. 05）. CONCLUSION： It＇s quite effective for early breast cancer patients to be performed the breast conserving surgery,which is better than the modified radical operation with lower recurrent rate. In addition,it also can ensure the beauty. In this case,it＇s worthy of application and promotion.