疏肝和胃法治疗2型糖尿病性胃轻瘫(肝胃不和证)86例临床观察

Clinical Observation of Applying Liver-soothing and Stomach-harmonizing Therapy to Treat 86 Cases of Type 2 Diabetic Gastroparesis(Liver and Stomach Disharmony Syndrome)

目的:以空白对照,评价疏肝和胃在治疗2型糖尿病性胃轻瘫(肝胃不和证)的有效性和安全性。方法:采用随机、平行对照的研究方法,以空白对照,评价疏肝健脾法治疗胃轻瘫(肝胃不和证)的安全性及有效性。本试验随机入组2型糖尿病性胃轻瘫(肝胃不和证)患者90例,试验过程中2例为脱落病例,2例为剔除病例。纳入分析86例(试验组56例,对照组30例)。结果:试验组疾病疗效显效率为67.86%、总有效率为92.86%;中医证候疗效显效率为60.72%、总有效率为92.86%;两组间差异有统计学意义(P<0.01),试验组优于对照组。试验过程中,未见明显不良反应。结论:疏肝和胃法改善2型糖尿病性胃轻瘫(肝胃不和)临床症状疗效确切。

Objective： Evaluating the effectiveness and safety of Liver- soothing and Stomach- harmonizing Therapy for Type 2diabetic gastroparesis（ disharmony between the liver and stomach） compared with blank controlled group. Methods： Using random and blank controlled method to evaluate the effectiveness and safety of Liver- soothing and Stomach- harmonizing Therapy. With 90 patients of Type 2diabetic gastroparesis（ disharmony between the liver and stomach） in total,and 2cases removed and 2cases excluded during the trial,eventually 86 cases were included in the analysis（ 56 cases in test group and 30 cases in controlled group）. Results： The obvious effective rate of the test group was 67. 86%,while the total effective was 92. 86%; the obvious effective rate of the TCM syndrome group was 60. 72%,while the total effective was 92. 86%; the differences between the two groups were significant（ P〈0. 01）,the test group was superior to the controlled group. No obvious harmful effect presented during experiment. Conclusion： According to the results of therapeutic effect,Liver- soothing and Stomach- harmonizing Therapy has definite therapeutic effect in improving clinical symptoms of Type 2diabetic gastroparesis（ disharmony between the liver and stomach）.