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琥珀酸脱氢酶缺陷型胃肠间质瘤研究进展 被引量:2

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摘要 琥珀酸脱氢酶(succinatedehydrogenase,SDH),又称复合物Ⅱ,是仅有的一个既参与三羧酸循环又参与电子传递链的催化酶,还是惟一在三羧酸循环中可在催化过程中发生底物水平磷酸化的催化酶。SDH是典型的抑癌基因,
出处 《中国实用外科杂志》 CSCD 北大核心 2016年第3期344-347,350,共5页 Chinese Journal of Practical Surgery
基金 上海市科委基金项目(No.12nm0501402) 上海市教委基金项目(No.120311)
关键词 琥珀酸脱氢酶 胃肠间质瘤 缺氧诱导因子 活性氧簇 succinate dehydrogenase gastrointestinal stromal tumors hypoxia inducible factor reactive oxygen species
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