中西医结合治疗老年女性泌尿系感染的疗效观察

Efficacy of traditional Chinese medicine combined western medicine on urinary tract infection in female senile patients

目的观察中西医结合治疗老年女性泌尿系感染的临床疗效,以探讨对老年女性泌尿系感染的更好药物治疗方案,从而提高治疗效果。方法选取于2014年1—12月医院收治的100例老年女性泌尿系感染患者,分为观察组和对照组,每组50例。对照组患者根据药敏的试验结果应用抗菌药物治疗,1周为一疗程,观察组在此基础上加用滋肾方加味汤剂治疗,1周为一疗程。2周后对比2组的临床疗效、症状改善时间、对血清超敏C反应蛋白影响和住院时间。结果观察组的总有效率为98.0%,显著高于对照组(80.0%),差异具有统计学意义(Z=3.375,P<0.01);观察组的尿频急和尿痛的缓解时间显著短于对照组,差异具有统计学意义(t=7.203,9.433,P<0.01);观察组治疗后血清超敏C反应蛋白降低明显优于对照组,差异具有统计学意义(t=12.141,P<0.01);观察组患者住院时间为(11.7±2.5)d,低于对照组的(16.2±2.8)d,差异具有统计学意义(P<0.05)。结论老年女性泌尿系感染在常规抗菌药物治疗的基础上加用中医药,能显著提高疗效,且症状改善明显,并降低血清中炎性介质水平,缩短患者住院时间,值得临床进一步推广。

Objective To explore the efficacy ofcombining traditional Chinese and western medicine in the treatment of urinary tract infection diseasein female patients,modify the dosage regime and improve the curative efficacy. Methods Total 100 cases of urinary tract infection disease in female senile patients in our hospital were randomly divided into observation group and control group with 50 cases in each group. The control group was received antibiotic treatment according to their drug susceptibility test results,and the observation group was given Traditional Chinese medicine based on the control group. The efficacy,symptoms improved time,CRP and length of stay in the two groups of patients were compared after two weeks treatment. Results The total effective rate in the observation group was 98. 0%,significantly higher than that in the control group（ 80. 0%）,the difference was statistically significant（ Z = 3. 375,P〈0. 01）; the relief time of Urinary frequency and urinary pain in observation group were significantly shorter than those of the control group,the difference was statistically significant t = 7. 203,9. 433,P〈0. 01）; The level of serum CRP reduced obviously when compared with the control group,the difference was statistically significant（ t = 12. 141,P〈0. 01）; In the observation group after the treatment,the length of stay was（ 11. 7 ± 2. 5） days,significantly less than that in the control group（ 16. 2 ± 2. 8） days,the difference was statistically significant（ P〈0. 05）. Conclusion Combining traditional Chinese and western medicine for urinary tract infection diseasein female senile patients had significant effect and less length of stay,and can significantly reduce the serum levels of inflammatory mediators,which is worthy of clinical promotion and research.