难治性哮喘支气管肺泡灌洗液细胞分类及气道病原菌定植、感染的状况

Classification of Bronchial Alveolar Lavage Fluid Cells in Patients With Refractory Asthma and the Status of Airway Pathogens Colonization and Infection

目的对难治性哮喘支气管肺泡灌洗液细胞分类及气道病原菌定植、感染的状况进行分析。方法选择我院收治的难治性哮喘患者100例作为研究对象,收治时间为2013年2月4日-2014年2月4日,通过支气管镜肺泡灌洗,对其细菌培养和支气管肺泡灌洗液细胞分类进行检测。结果支气管肺泡灌洗液细胞共分为中性粒细胞、嗜酸粒细胞、淋巴细胞、肺泡巨噬细胞,其中中性粒细胞明显增高。结论难治性哮喘患者气道炎症细胞具有典型的炎症表现,且以中性粒细胞增多为特征,该现象与细菌的感染和定植密切相关。

Objective To analyze the classification of bronchial alveolar lavage fluid cells in patients with refractory asthma, and to analyze the status of airway pathogens colonization and infection. Methods 100 cases of refractory asthma patients who were treated in our hospital as the research object from February 4, 2013 to February 4, 2014, by bronchoalveolar lavage, the bacterial cultures and bronchoalveolar lavage cell classification were detected. Results The cells were divided into neutrophils, eosinophils, lymphocytes and alveolar macrophages, and neutrophils were significantly increased. Conclusion Airway inflammatory cells in patients with refractory asthma have typical inflammatory features, and the phenomenon is closely related to bacterial infection and colonization.