23价肺炎球菌多糖疫苗和流感疫苗联合接种对慢性阻塞性肺病患者防治的疗效观察

Observation on 23 Valent Pneumococcal Polysaccharide Vaccine and Influenza Vaccine Inoculation in Prevention and Treatment of Patients With Chronic Obstructive Pulmonary Disease

目的探讨23价肺炎球菌多糖疫苗联合流感疫苗接种在预防和治疗慢性阻塞性肺病患者中的作用。方法收集我市某院2013年12月-2015年12月治疗的240例患者,随机分成观察组和对照组各120例,对照组给予解痉平喘,化痰止咳、消炎等对症治疗,观察组在对照组的基础上注射流感疫苗和23价肺炎链球菌疫苗。结果两组患者发作次数、发作时间、住院次数、住院时间和死亡例数比较差异有统计学意义（P〈0.05）。结论慢性阻塞性肺病患联合接种23价肺炎球菌多糖疫苗和流感疫苗,疗效佳。

Objective To investigate the 23-valent pneumococcal polysaccharide vaccine combined influenza vaccination in prevention and treatment of in patients with chronic obstructive pulmonary disease. Methods In our hospital from December 2013 to December 2015,240 cases were randomly divided into observation group and control group. 120 cases of the control group was given antispasmodic,anti-inflammatory and other symptomatic treatment,the observation group on the basis of the control group grven influenza vaccine and 23-valent pneumococcal vaccine. Results The seizure frequency,time of onset,number of hospitalizations,length of stay and number of deaths of difference was statistically significant（P〈0.05）. Conclusion Patients with chronic obstructive pulmonary inoculation joint 23-valent pneumococcal polysaccharide vaccine and influenza vaccine,have a significant effect.