急性肾功能衰竭患者的临床治疗方法及临床治疗体会

Clinical Treatment Methods and Experience of Patients With Acute Renal Failure

目的研究急性肾功能衰竭患者中西医结合治疗的临床效果。方法入选我院2014年6月-2015年6月肾内科因急性肾衰住院的患者76例,将患者随机分为试验组和对照组,每组各38例,对照组给予常规西医综合治疗,试验组在西医综合治疗的基础上给予血必净注射液50 ml,每天2次,静滴。观察患者症状的改善情况,尿量的改变情况,血肌酐、血尿素氮的改变时间。结果对照组临床治疗有效率为78.95%,试验组临床治疗有效率94.74%,两组患者的总治疗有效率差异具有统计学意义（P〈0.05）。试验组的尿蛋白转阴时间低于对照组,差异具有统计学意义（P〈0.05）;血肌酐及尿素氮降至正常时间分别为（15.33±5.89）d,（27.19±8.22）d,两组比较差异具有统计学意义,P〈0.05。结论本研究显示,血必净注射液应用于临床急性肾功能衰竭的治疗,能改善患者的症状,对肾小管的坏死具有保护作用。

Objective To study the clinical effect of combined treatment of traditional Chinese and Western medicine in acute renal failure patients. Methods selected department of nephrology for 76 cases of patients with acute renal failure hospitalized,in our hospital from June 2014 to June 2015,were randomly divided into experimental group and control group,with 38 cases in each. The control group was treated with routine western medicine therapy,experimental group on the basis of integrated traditional Chinese and Western medicine therapy given Xuebijing injection 50 ml,2 times a day,intravenous infusion. To observe the improvement of patients＇ symptoms, changes of urine volume,blood creatinine and blood urea nitrogen. Results The clinical effective rate of the control group was 78.95%,the clinical effective rate was 94.74% in experimental group,the total effective rate of the two groups was statistically significant（P〈0.05）. Experimental group of urine protein clearance time was significantly lower than that of the control group,the difference was statistically significant（P〈0.05）. Blood urea nitrogen and creatinine fell to normal time of difference between the two groups had statistical significance（15.33±5.89）d,（27.19±8.22）d,P〈0.05. Conclusion This study showed that,the application of Xuebijing injection in the treatment of acute renal failure,the curative effect is remarkable,can significantly improve the patient＇s symptoms and necrosis of renal tubules.