摘要
围绝经期综合征尤其是潮热严重影响女性身心健康和生活质量。选择性5-羟色胺再摄取抑制剂是一类能够抑制5-羟色胺再摄取,增加突触间隙5-羟色胺浓度的一类药物,这类药物在临床上主要用于抑郁症的治疗,但近年来发现其亦能有效地缓解围绝经期潮热的症状。本文就选择性5-羟色胺再摄取抑制剂对潮热的治疗作用做一综述。
Perimenopausal symptom especially hot flash has a serious effect on women 's mental health and life quality. Selective serotonin reuptake inhibitors( SSRI) are medicines which inhibit reuptake of serotonin thus increasing the concentration of serotonin on synaptic cleft.These medicines are used for treating dipression. Recent studies found that they could also alleviate perimenopausal hot flash. In this paper we will review the effect of SSRIs on treating hot flash.
出处
《中国临床药理学杂志》
CAS
CSCD
北大核心
2016年第5期476-478,共3页
The Chinese Journal of Clinical Pharmacology
基金
国家自然科学基金资助项目(81270666)