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老年晚期非小细胞肺癌患者预后新独立影响因素——预后营养指数 被引量:14

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摘要 目的:分析老年晚期非小细胞肺癌(NSCLC)的临床病理特征及预后相关影响因素。方法:回顾性分析86例老年晚期NSCLC患者的临床资料,采用Kaplan—Meier法估计生存率并进行单因素分析,Cox比例风险回归模型多因素分析评估患者临床病理特征、治疗方式、预后营养指数(PNI)等因素对生存期的影响.结果:86例患者均为Ⅲ-Ⅳ期的NSCLC.确诊肺癌后1、2、3年生存率分别为33.7%、22.1%、9.3%,中位生存时间为12.5个月。单因素分析结果显示年龄、肿瘤TNM分期、KPS评分、简化合并症评分、预后营养指数(PNI)值、治疗方式与患者预后有关。Cox多因素分析显示KPS〈70分、SCS〉9分、PNI〈45和仅接受辅助支持治疗是影响老年晚期NSCLC患者的独立预后危险因素。结论:PNI值是一个新的老年晚期NSCLC预后独立影响因素.对患者预后判断有重要的提示作用。
出处 《实用医学杂志》 CAS 北大核心 2016年第3期460-462,共3页 The Journal of Practical Medicine
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