低钠血症与骨质疏松及骨折的关系

Relationship of hyponatremia with osteoporosis and fractures

低钠血症是临床最常见的电解质紊乱。除神经系统并发症外，低钠血症的其他并发症没有得到足够重视。轻度、慢性低钠血症常导致患者的步态不稳、跌倒，并能增加骨质疏松和骨折风险。本文拟对低钠血症与骨代谢的密切关系、可能机制及临床意义进行综述。

Hyponatremia is the most common electrolyte imbalance. Other than neurological complica- tions, other complications of hyponatremia have not received due attention. Mild, chronic hyponatremia can re- sult in subtle symptoms such as gait disturbance and fails, and increase the risks of osteoporosis and fractures. This paper reviewed the emerging relationship between hyponatremia and bone metabolism, its possible mecha- nisms and clinical implications.